Multi-Year Research Grants and Personnel Awards (July 1, 2008 to June 30, 2009) - Release of Funds

The Heart and Stroke Foundation of Ontario is pleased to announce confirmation of budget commitment on existing multi-year grants-in-aid and personnel awards as indicated below. An official letter will also be sent to all grant recipients shortly. For those awards identified as "pending"", funding is encumbered until additional information is provided.

Additionally, for projects that were identified as being "applied" or "clinically oriented" in the September 2006 competition, funding is encumbered pending the May 15, 2008 Progress Report. For all other awards, please refer to your award letter for details. 
 

September 2007 Competition Funding Decisions

The funding decisions for the September 2007 competition will be announced by March 15, 2008 on the national website www.hsf.ca/research.
  • Adeli, Khosrow (Hospital for Sick Children)
    Molecular mechanisms of apolipoprotein B degradation
    2005, Renewal, $117,860
     
  • Adeli, Khosrow (Hospital for Sick Children)
    Molecular mechanisms of hepatic VLDL overproduction in insulin resistance
    2007, Renewal, $138,235
     
  • Al-Hesayen, Abdul O. (St. Michael's Hospital)
    Exploring the role of cGMP in human heart failure
    2007, Clinician Scientist (Pending) $64,000
     
  • Alter, David A. (St. Michael's Hospital)
    Cardiovascular treatment & outcomes disparities among high-risk populations
    2006, Career Investigator, $87,950
     
  • Anand, Sonia (McMaster University)
    EpiDREAM - A prospective cohort study to determine environment and genetic determinants of metabolic syndrome related factors
    2006, New Annual, $161,495
     
  • Andrew, R. David (Queen's University)
    Imaging and preventing early stroke damage in intact mammalian neurons
    2006, Renewal, $74,328
     
  • Askalan, Rand (Hospital for Sick Children)
    Neuroprotection by inhibitors of apoptosis proteins following neonatal stroke
    2007, Clinician Scientist (Pending), $64,000
     
  • Athale, Uma H. (McMaster University)
    Evaluation for inherited and acquired prothrombotic defects predisposing to symptomatic thromboembolism in children with acute lymphoblastic leukemia
    2007, New Annual (Pending), $40,351
     
  • Atzema, Clare (Sunnybrook Health Sciences Center)
    Emergency department triage and time to ECG: the effect on reperfusion delays for AMI patients
    2007, Clinician Scientist (Pending), $64,000
     
  • Austin, Richard C. (McMaster University)
    Role of endoplasmic reticulum stress in atherothrombotic disease
    2006, Career Investigator, $87,950
     
  • Austin, Richard C. (McMaster University)
    Role of the sterol regulatory element-binding proteins in foam cell formation and atherogenesis
    2007, New Annual, $94,877
     
  • Austin, Richard C. (McMaster University)
    Inhibition of tissue factor procoagulant activity by GRP78 and its role in thrombosis
    2007, Renewal, $87,471
     
  • Backx, Peter H. (University of Toronto)
    Mechanisms of heart disease
    2004, Career Investigator, $87,950
     
  • Bartha, Robert (Robarts Research Institute)
    New metabolic imaging approaches to assess brain tissue viability
    2006, Renewal, $85,645
     
  • Beanlands, Rob S. B. (University of Ottawa Heart Institute)
    Elucidation of metabolic and cellular function alterations in dysfunctional myocardium and their response to therapy
    2007, Program, $249,828
     
  • Belik, Jaques (Hospital for Sick Children)
    ENOS uncoupling and role of bone morphogenetic protein-9 in the regulation of pulmonary vascular tone during development and following pulmonary hypertension
    2007, New Annual, $87,725
     
  • Bendeck, Michelle P. (University of Toronto)
    Smooth muscle cell interactions with the extracellular matrix in atherosclerosis
    2004, Career Investigator, $87,950
     
  • Bendeck, Michelle P. (University of Toronto)
    Discoidin domain receptors (DDR1) in atherosclerosis
    2007, New Annual, $84,860
     
  • Billia, Filio (University of Toronto)
    Regulation of cardiac muscle growth and proliferation by cytoplasmic p27K1P1
    2007, Clinician Scientist (Pending), $64,000
     
  • Birnie, David H. (University of Ottawa Heart Institute)
    Importance of mechanical dyssynchrony and resynchronization therapy in heart failure patients
    2006, Clinician Scientist (Pending), $70,250
     
  • Boffa, Michael B. (Queen's University)
    The TAFI pathway in thrombolysis: regulation of TAFI activation and role of the platelet pool of TAFI
    2006, New Annual, $90,969
     
  • Bolz, Steffen-Sebastian (University of Toronto)
    Mechanisms that regulate the pressure-dependent activation of the sphingosine-1-phosphate signalling pathway in resistance arteries
    2007, New Annual, $70,190
     
  • Bonen, Arend (University of Guelph)
    Regulation of fatty acid transport in the heart
    2006, Renewal, $97,646
     
  • Bose, Arpita (University of Windsor)
    Recovery in post-stroke aphasia: psycholinguistics and psychosocial perspective
    2006, Fellowship, $47,500
     
  • Boughner, Derek R. (University of Western Ontario)
    A tissue engineering approach to bioprosthetic heart valve design
    2006, New Annual, $95,398
     
  • Bradley, Timothy J. (Hospital for Sick Children)
    Inflammation and atherosclerosis in pediatric rheumatic diseases
    2007, New Annual, $66,045
     
  • Brooks, Dina (University of Toronto)
    Cardic rehabilitation after stroke
    2006, Stroke Rehabilitation (Pending), $68,479
     
  • Brouwer, Brenda (Queen's University)
    Client-centred 'tune-ups': do they enhance physical capacity, mobility function and community reintegration in stroke survivors?
    2006, Stroke Rehabilitation (Pending), $204,206
     
  • Caldarone, Christopher A. (Hospital for Sick Children)
    Apoptosis-related mitochondrial dysfunction in the neonate after cardioplegic arrest
    2007, New Annual (Pending), $117,116
     
  • Cepinskas, Gediminas (London Health Sciences Centre)
    Cerebrovascular endothelial cell dysfunction in sepsis: role of astrocytes
    2007, New Annual, $82,747
     
  • Chan, Anthony K.C. (McMaster University)
    Study of the pathogenesis and treatment of pediatric disease related to the hemostatic system
    2005, Career Investigator, $87,950
     
  • Chan, Anthony K.C. (McMaster University)
    Surface mechanisms of anticoagulant ATH complex
    2007, Renewal, $86,139
     
  • Chauhan, Vijay S. (University Health Network)
    Characterizing ventricular repolarization alternans in human cardiomyopathy
    2007, Renewal, $84,004
     
  • Chauhan, Vijay S. (University Health Network)
    Characterizing ventricular repolarization alternans in human cardiomyopathy
    2007, Clinician Scientist (Pending), $70,250
     
  • Cote, Graham P. (Queen's University)
    Formation and function of invadopodia in vascular smooth muscle cells
    2007, Renewal, $90,618
     
  • Crowther, Mark A. (McMaster University)
    Optimizing anticoagulant therapy
    2004, Career Investigator, $87,950
     
  • Crowther, Mark A. (McMaster University)
    Evaluating the incidence and clinical importance of heparin induced thrombocytopenia in the critically ill
    2007, New Annual (Pending), $65,006
     
  • Cybulsky, Myron I. (University Health Network)
    Regional differences in the arterial intima that predispose the artery wall to atherogenesis
    2007, Renewal, $104,659
     
  • Cybulsky, Myron I. (University Health Network)
    Monocyte recruitment in atherosclerosis
    2007, Renewal, $116,845
     
  • Cybulsky, Myron I. (University Health Network)
    Initiation of atherosclerosis: mechanisms and cell biology
    2007, Career Investigator, $87,950
     
  • Devereaux, Philip J. (McMaster University)
    Vascular events in noncardiac surgery patients cohort (VISION) study
    2007, New Annual (Pending), $95,242
     
  • Drangova, Maria (Robarts Research Institute)
    Cardiac imaging for therapy guidance and pre-clinical research studies
    2007, Career Investigator, $87,950
     
  • D'Souza, Sudhir J.A. (University of Western Ontario)
    Integrin-linked kinase and elmo in endothelial migration and phagocytosis
    2007, New Annual, $67,744
     
  • Dumont, Daniel J. (Sunnybrook Health Sciences Center)
    Molecular studies examining the role of lymphangiogenic signalling in heart disease
    2007, Renewal, $84,900
     
  • Epand, Richard M. (McMaster University)
    Development of potent antiatherogenic peptides
    2007, New Annual (Pending), $79,250
     
  • Eubanks, James H. (University Health Network)
    Methyl DNA-binding factor complexes and neurodegeneration
    2006, New Annual, $86,102
     
  • Feindel, Christopher M. (University Health Network)
    Erythropoietin and hypertonic saline for cardiac transplant
    2006, Renewal, $92,900
     
  • Feldman, Ross D. (Robarts Research Institute)
    Determinants of adenylyl cyclase mediated vascular responses
    2007, New Annual, $110,850
     
  • Feldman, Ross D. (Robarts Research Institute)
    Acute vascular effects of aldosterone
    2007, New Annual, $78,016
     
  • Feng, Qingping (University of Western Ontario)
    Mechanisms of heart failure
    2005, Career Investigator, $87,950
     
  • Feng, Qingping (London Health Sciences Centre)
    Cardioprotection by erythropoietin: role of nitric oxide
    2007, Renewal, $122,126
     
  • Feng, Zhong-Ping (University of Toronto)
    Modulatory mechanisms underlying expression of cardiac voltage-dependent calcium channels
    2006, Renewal, $62,250
     
  • Ferguson, Alastair (Queen's University)
    Adiponectin actions in autonomic control centres of the brain
    2007, Renewal, $120,661
     
  • Ferguson, Stephen G. (Robarts Research Institute)
    Regulation of G protein-coupled receptor signaling desensitization and resensitization
    2006, Renewal, $123,041
     
  • Flamengo, Maria F. (University of Western Ontario)
    Associating baseline levels of medial prefrontal cortex activity with autonomic cardiovascular control
    2007, Master's Studentship (Pending), $18,000
     
  • Floras, John S. (University of Toronto)
    Cardiovascular regulation in men and women with heart failure and hypertension
    2006, Career Investigator, $43,975
     
  • Fremes, Stephen E. (Sunnybrook Health Sciences Center)
    Unraveling the black box of adverse events in cardiac surgery
    2006, Renewal, $88,850
     
  • Funk, Colin D. (Queen's University)
    COX-2 pathway and cardiovascular disease
    2006, New Annual, $119,470
     
  • Funk, Colin D. (Queen's University)
    Lipoxygenase and cyclooxygenase pathways in cardiovascular disease
    2006, Career Investigator, $87,950
     
  • Gaisano, Herbert Y. (University of Toronto)
    SNARE regulation of cardiac sulfonylurea receptor. a novel drug target for cardiac ischemia
    2007, Renewal, $101,479
     
  • Gao, Yu-Jing (McMaster University)
    Perivascular adipose tissue, reactive oxygen species and hypertension
    2007, New Annual, $74,460
     
  • Gilbert, Richard E. (St. Michael's Hospital)
    Pathogenetic role of protein kinase c-beta in diabetic cardiomyopathy: interventional and translational studies
    2007, New Annual, $110,085.56 
     
  • Ginsberg, Jeffrey S. (McMaster University)
    Diagnosis and management of thromboembolic disorders in multiple patient populations
    2007, Career Investigator, $87,950
     
  • Gladstone, David J. (Sunnybrook Health Sciences Center)
    Stroke prevention for high-risk patients: Identifying barriers and creating solutions
    2006, Clinician Scientist (Pending), $64,000
     
  • Gollob, Michael H. (University of Ottawa Heart Institute)
    Pathophysiologic study of the role of AMPK in cardiac arrhythmias, conduction system development, and metabolic cardiomyopathy
    2006, Renewal, $79,531
     
  • Gollob, Michael H. (University of Ottawa Heart Institute)
    Genetic determination of atrial fibrillation
    2006, Clinician Scientist (Pending), $64,000
     
  • Gorczynski, Reginald M. (University Health Network)
    Regulation of transplant rejection and inflammation in CD200tg and CD200R KO mice
    2007, New Annual, $92,208
     
  • Gotlieb, Avrum I. (University Health Network)
    Cell biology of heart valve interstitial cells
    2007, New Annual, $90,516
     
  • Graham, Charles H. (Queen's University)
    Mechanisms regulating the development and pathophysiology of pre-eclamptic hypertension
    2007, Renewal, $96,792
     
  • Grinstein, Sergio (Hospital for Sick Children)
    Dual role of CD36 in macrophages: atherosclerosis and immune responsiveness
    2006, Renewal, $87,596
     
  • Gross, Gil J. (Hospital for Sick Children)
    Ventricular repolarization in bradycardic electrical remodeling
    2007, Renewal, $89,674
     
  • Gross, Peter L. (McMaster University)
    Defining how atorvastatin inhibits platelets
    2007, New Annual, $75,148
     
  • Grover, Ashok K. (McMaster University)
    Effects of reactive oxygen on Na-Ca exchange in coronary artery
    2007, Renewal, $101,514
     
  • Gupta, Radhey S. (McMaster University)
    Studies on mammalian adenosine kinase and its inhibitors
    2007, 
    Renewal, $87,879
     
  • Haas, Tara L. (York University)
    The regulation of angiogenic factors by shear stress
    2007, New Annual, $79,750
     
  • Hache, Robert J.G. (Ottawa Health Research Institute)
    Regulation of human primary preadipocyte differentiation by glucocorticoids
    2006, Renewal, $93,779
     
  • Han, Kristina (Queen's University)
    The cellular biochemistry of apolipoprotein(a) secretion: relationship between Apo(a) size and secretion efficiency
    2007, Master's Studentship (Pending), $18,000
     
  • Harper, Mary-Ellen (University of Ottawa)
    Novel AMPK-gamma mutations in humans: implications for skeletal muscle energy metabolism
    2007, New Annual (Pending), $100,324
     
  • Hayward, Catherine P. (McMaster University)
    Studies of novel platelet and vascular secretory proteins
    2005, 
    Career Investigator, $87,950
     
  • Hayward, Catherine P. (McMaster University)
    Structure-function analysis of multimerin 1 proadhesive function
    2006, Renewal, $93,251
     
  • Hayward, Catherine P. (McMaster University)
    Studies of the mechanisms involved in generating profibrinolytic and antifibrinolytic human platelets
    2006, Renewal, $82,299
     
  • Hegele, Robert A. (Robarts Research Institute)
    Phenomics and genomics of atherosclerosis in monogenic metabolic syndrome
    2007, Renewal, $110,723
     
  • Hegele, Robert A. (Robarts Research Institute)
    Genomics of hypertriglyceridemia
    2007, New Annual (Pending), $110,372
     
  • Heximer, Scott P. (University of Toronto)
    Defining the role of RGS2 as a mediator of vascular signaling and blood pressure regulation
    2006, Renewal, $109,623
     
  • Hou, Sheng T. (University of Ottawa)
    Semaphorin-3A's role in axonal degeneration and regeneration following cerebral ischemia
    2006, Renewal, $65,392
     
  • Hough, Margaret R. (Sunnybrook Health Sciences Center)
    Cardiac repair and regeneration
    2006, New Annual, $91,113
     
  • Huff, Murray W. (University of Western Ontario)
    Regulation of ApoB metabolism: relationship to atherosclerosis
    2005, RenewaL, $136,879
     
  • Huff, Murray W. (Robarts Research Institute)
    Cellular Programs and Responses in Atherosclerosis
    2006, Program, $250,000
     
  • Husain, Mansoor (University of Toronto)
    Molecular regulation of vascular smooth muscle cell proliferation and contractility
    2004, Career Investigator, $87,950
     
  • Husain, Mansoor (University Health Network)
    Role of glucagon-like peptides in cardiac health and disease
    2006, New Annual, $116,909
     
  • Hutchison, James Sanders (Hospital for Sick Children)
    Adhesion receptors following global cerebral ischemia: Role of adhesion receptor blockade/knockout and hypothermia therapy
    2007, New Annual (Pending), $71,380
     
  • Ikura, Mitsuhiko (University Health Network)
    Structural elucidation of intracellular calcium transporters
    2006, 
    Renewal, $102,377
     
  • Kahr, Walter H.A. (Hospital for Sick Children)
    The role of VPS33B in platelet alpha granule formation
    2006, Clinician Scientist (Pending), $70,250
     
  • Karmazyn, Morris (University of Western Ontario)
    Modulation of cardiomyocyte hypertrophy by nitric oxide and endothelin-1 in the aging myocardium
    2005, Renewal, $102,526
     
  • Karmazyn, Morris (University of Western Ontario)
    Role of adenosine in myocardial hypertrophy and heart failure
    2007, New Annual, $95,610
     
  • Kawaja, Michael David (Queen's University)
    Evaluating phenotypic changes in cerebral vessels of stroke-prone spontaneously hypertensive rats: a pilot proteomic investigation
    2007, New Annual (Pending), $68,042
     
  • Keeley, Fred W. (Hospital for Sick Children)
    Recombinantly expressed polypeptides of human elastin as a novel tool for investigations of the structure, self-assembly and properties of elastin-like materials
    2004, Renewal, $115,923
     
  • Kelton, John G. (McMaster University)
    Platelet-mediated acute thrombotic disorders
    2005, Renewal, $149,413
     
  • Khokha, Rama (University Health Network)
    Molecular dissection of the distinct function of TIMP-3 and TIMP-4 in heart disease
    2006, Renewal, $75,861
     
  • Ko, Dennis T. (Sunnybrook Health Sciences Center)
    Appropriateness and necessity of coronary angiogram
    2006, Clinician Scientist (Pending), $64,000
     
  • Koschinsky, Marlys L. (Queen's University)
    Interaction of Lp(a) with the plasminogen system: mechanisms and pathophysiological consequences
    2005, Renewal (Pending), $101,667
     
  • Koschinsky, Marlys L. (Queen's University)
    The pathophysiology of Lp(a) in the arterial wall: effect of Apo(a) on vascular cell function
    2006, Renewal, $100,600
     
  • Koschinsky, Marlys L. (Queen's University)
    Mechanisms of atherothrombosis: analysis of lipoprotein and fibrinolytic risk factors
    2006, Career Investigator, $87,950
     
  • Krahn, Andrew D. (University of Western Ontario)
    Clinical and genetic assessment of primary electrical disease
    2006, Renewal, $97,231
     
  • Kutryk, Michael J. B. (St. Michael's Hospital)
    Novel application of progenitor endothelial cells
    2006, Clinician Scientist (Pending), $70,250
     
  • Langille, B. Lowell (University of Toronto)
    Cell Biology of Atherosclerosis
    2005, Program, $250,000
     
  • Langille, B. Lowell (University Health Network)
    Arterial responses to hemodynamic stresses
    2007, Renewal, $91,308
     
  • Langille, B. Lowell (University Health Network)
    Cadherins and regulation of smooth muscle cell function
    2007, Renewal, $125,957
     
  • Letarte, Michelle V. (Hospital for Sick Children)
    Role of endoglin in normal vasculature and in the pathology of HHT
    2005, Renewal, $95,321
     
  • Levin, Mindy F. (University of Ottawa)
    Optimizing arm motor recovery in stroke
    2007, New Annual (Pending), $33,100
     
  • Li, Ren-Ke (University Health Network)
    Restoration of cardiac function: cellular regeneration and matrix reconstruction
    2006, Career Investigator, $87,950
     
  • Li, Ren-Ke (University Health Network)
    Matrix modulation is required to restore cardiac function after cell therapy
    2007, Renewal, $94,497
     
  • Linkins, Lori-Ann (McMaster University)
    Improving the diagnosis of heparin-induced thrombocytopenia: utility of the 4T's score and evaluation of new rapid assays
    2007, New Annual (Pending), $103,722
     
  • Liu, Peter P. (University Health Network)
    "Danger signal", cell injury and "innate immune response" in regulating inflammation in cardiovascular disease
    2005, Renewal (Pending), $111,062
     
  • Liu, Peter P. (University Health Network)
    Homing signals and cell mobilization in cardiac remodeling post myocardial infarction
    2006, Renewal, $98,341
     
  • Logan, Alexander G. (Mount Sinai Hospital)
    Self-monitoring of blood pressure in primary care in older (45+ years) diabetic patients with uncontrolled systolic hypertension
    2006, Elevated Systolic (Pending), $204,003
     
  • Lucas, Alexandra R. (Robarts Research Institute)
    Serpin regulation of innate immune response and vascular repair
    2006, Renewal, $78,892
     
  • Mak, Alan S. (Queen's University)
    Cortactin and caldesmon in vascular smooth muscle cell migration and invasion
    2006, Renewal, $96,865
     
  • Marcel, Yves L. (University of Ottawa Heart Institute)
    The genetic basis of cholesterol efflux defects in hypoalphalipoproteinemia
    2006, Renewal, $94,746
     
  • Marsden, Philip A. (University of Toronto)
    Post-transcriptional regulation of eNOS expression
    2005, Renewal, $95,069
     
  • Marsden, Philip A. (University of Toronto)
    Regulated expression of the human nNOS gene
    2006, Renewal, $112,578
     
  • Maurice, Donald H. (Queen's University)
    PDEs in blood vessels
    2006, Career Investigator, $87,950
     
  • McCulloch, Christopher A. (University of Toronto)
    Regulation of myofibroblast differentiation by mechanical loading
    2007, Renewal, $98,082
     
  • McNicholl, Eric T. (McMaster University)
    Structural basis for the cAMP signal translation in PKA by NMR
    2007, Master's Studentship (Pending), $18,000
     
  • McPherson, Ruth (University of Ottawa Heart Institute)
    Genetic determinants of HDL-C
    2007, New Annual (Pending), $134,607
     
  • Megeney, Lynn A. (Ottawa Health Research Institute)
    Caspase mediated induction of cardiac hypertrophy
    2007, New Annual (Pending), $81,066
     
  • Milne, Ross W. (University of Ottawa Heart Institute)
    Advanced glycation end products and diabetic atherosclerosis
    2007, Renewal, $69,794
     
  • Morris, Catherine E. (Ottawa Health Research Institute)
    The mechanosensitivity of pacemaker channels
    2007, New Annual, $80,914
     
  • Myers, Martin G. (Sunnybrook Health Sciences Center)
    Automated office blood pressure measurement
  • 2005, Elevated Systolic (Pending), $358,043
     
  • Nag, Sukriti (University Health Network)
    Regulation of cerebrovascular homeostasis and repair by angiogenic factors
    2007, Renewal, $89,595
     
  • Nesheim, Michael E. (Queen's University)
    The activation of TAFI and the properties of TAFIa
    2005, Renewal (Pending), $90,699
     
  • Nowacki, Nathaniel B. (York University)
    Regulation of MEF2 activity in cardiac myocytes
    2007, Master's Studentship (Pending), $18,000
     
  • Nurse, Colin A. (McMaster University)
    Mechanisms regulating asphyxial responses in rat adrenal chromaffin cells
    2006, Renewal, $84,325
     
  • Ofosu, Frederick A. (McMaster University)
    Platelet-derived serine proteases and platelet activation
    2007, Renewal, $70,398
     
  • Opas, Michal J. (University of Toronto)
    Calreticulin: cell and developmental biology
    2007, Renewal, $107,923
     
  • Opavsky, Mary Anne (Hospital for Sick Children)
    Heart failure and the coxsackie-adenovirus receptor (CAR): insights through a novel heart targeted CAR transgenic mouse
    2007, Renewal, $92,114
     
  • Opavsky, Mary Anne (Hospital for Sick Children)
    The coxsackie-adenovirus receptor in heart infection and heart failure
    2007, Clinician Scientist (Pending), $70,250
     
  • Pak, Melissa (Queen's University)
    Dysfunctional muscle blood flow regulation during exercise in type II diabetes
    2007, Master's Studentship (Pending), $18,000
     
  • Pandey, Siyaram (University of Windsor)
    Identification and functional characterization of unique single domain intrabodies against pro-apoptotic proteins and their application in the discovery of novel pharmacophore
    2006, Renewal, $61,000
     
  • Pang, Stephen C. (Queen's University)
    Hypoxia inducible expression of atrial natriuretic peptide: a potential preemptive therapy for myocardial infarction
    2007, Renewal, $84,452
     
  • Park, David S. (University of Ottawa)
    Mechanisms of delayed death in stroke
    2004, Renewal, $80,600
     
  • Park, David S. (Ottawa Health Research Institute)
    Pathways which regulate neuronal death
    2006, Career Investigator, $87,950
     
  • Parker, John D. (University of Toronto)
    Clinical studies concerning nitrate pharmacology and autonomic physiology in congestive heart failure
    2007, Career Investigator, $87,950
     
  • Parkinson, John (Hospital for Sick Children)
    A combined theoretical/experimental approach to understanding sequence-structure-function relationships in elastin
    2007, Renewal, $58,548
     
  • Peng, Tianqing (London Health Sciences Centre)
    PLCgamma/IP3 signaling regulates cardiac TNF-alpha expression in sepsis
    2006, New Annual, $98,805
     
  • Pickering, J. Geoffrey (Robarts Research Institute)
    Regulation of smooth muscle cell differentiation and longevity
    2005, Renewal, $107,295
     
  • Popovic, Milos R. (Toronto Rehabilitation Institute)
    Functional electrical stimulation-assisted walking: enhancement of voluntary walking function among persons with severe hemiplegia post stroke
    2006, Stroke Rehabilitation (Pending), $32,265
     
  • Radisic, Milica (University of Toronto)
    Peptide modified photocrosslinkable chitosan for cell therapy in myocardial infarction
    2007, New Annual, $52,154
     
  • Rand, Margaret L. (Hospital for Sick Children)
    The procoagulant surface of activated platelets: persistence in vitro and in vivo
    2007, Renewal, $87,521
     
  • Reid, Robert D. (University of Ottawa Heart Institute)
    An interactive, voice response-mediated, follow-up and triage system for smoking cessation in smokers with CHD
    2006, New Annual, $33,312
     
  • Reid, Robert D. (University of Ottawa Heart Institute)
    Efficacy and cost-effectiveness of behavioural counselling for exercise behaviour in men and women following AMI and PCI
    2007, Renewal, $73,375
     
  • Reid, Robert D. (University of Ottawa Heart Institute)
    A program to reduce cardiovascular risk among family members of patients with coronary heart disease
    2007, New Annual (Pending), $93,050
     
  • Robinson, Lisa A. (Hospital for Sick Children)
    Regulation of the membrane-anchored chemokine, fractalkine, by thromboxane A2
    2007, Renewal, $89,480
     
  • Rochon, Elizabeth A (University of Toronto)
    Understanding the behavioural, neural and communicative changes underlying the treatment for anomia in aphasia
    2007, Renewal, $92,328
     
  • Rodger, Marc A. (Ottawa Health Research Institute)
    Thrombophilia and placenta mediated pregnancy complications
    2007, Career Investigator, $87,950
     
  • Roy, Eric A. (University of Waterloo)
    Neuropsychological profiles and neuroanatomic correlates of limb apraxia
    2007, Renewal, $69,864
     
  • Rush, James W.E. (University of Waterloo)
    Vascular endothelium adaptations to hypertension and exercise
    2007, Renewal, $73,831
     
  • Sandig, Martin (University of Western Ontario)
    Integrin signaling in monocyte transendothelial migration
    2007, New Annual, $84,265
     
  • Schlichter, Lyanne C. (University Health Network)
    Novel strategies to regulate microglia activation and neurotoxicity
    2006, Renewal, $86,963
     
  • Seibert, Tara A. (University of Ottawa)
    Understanding the vascular protective mechanisms of an estrogen- inducible protein using gene expression profiling
    2007, Master's Studentship (Pending), $18,000
     
  • Shaughnessy, Stephen G. (McMaster University)
    Mechanisms of vascular calcification in diabetes mellitus
    2007, New Annual (Pending), $78,729
     
  • Sheffield, William P. (McMaster University)
    The clot-targeting properties of natural and engineered antiplasmins
    2006, Renewal, $83,308
     
  • Sherifali, Diana T. (McMaster University)
    Appraisal of a community approach to facilitated self-management of diabetes mellitus
    2007, Nursing Fellowship, $59,000
     
  • Shikatani, Eric A. (York University)
    Cellular mechanisms underlying corticosterone-dependent inhibition of angiogenesis
    2007, Master's Studentship (Pending), $18,000
     
  • Silverman, Earl D. (Hospital for Sick Children)
    Role of chronic inflammation and systemic lupus erythematosus-related factors in the development of premature atherosclerosis in pediatric SLE
    2006, Renewal, $136,843
     
  • Simmons, Craig A. (University of Toronto)
    The role of extracellular matrix biomechanics in aortic valve sclerosis
    2007, New Annual, $83,235
     
  • Siu, Samuel C. (University Health Network)
    Neurodevelopmental outcomes in offsprings of women with heart disease
    2007, Renewal, $40,070
     
  • Slack, Ruth (Ottawa Health Research Institute)
    Regulation of Mcl1 to treat stroke
    2006, Renewal, $101,388
     
  • Slack, Ruth (Ottawa Health Research Institute)
    Mitochondrial dynamics in neuronal injury
    2007, New Annual, $109,773.20
     
  • Smith, Steven P. (Queen's University)
    Lipoprotein(a) in atherosclerosis: assembly and interaction with extracellular matrix proteins
    2007, Renewal, $130,119
     
  • Sorisky, Alexander (Ottawa Health Research Institute)
    Pro-atherogenic responses of human adipocytes to TSH
    2007, Renewal, $93,039
     
  • Sparks, Daniel L. (University of Ottawa Heart Institute)
    Regulation of ApoA-I synthesis and secretion by phoshatidylinositol
    2006, New Annual, $101,836
     
  • Spears, Julian (St. Michael's Hospital)
    International, prospective, multi-center study of radiographic and clinical events in the management of cerebral aneurysms >= 1cm
    2006, Clinician Scientist (Pending), $64,000
     
  • Spence, J. David (Robarts Research Institute)
    3D Ultrasound phenotypes and vascular risk
    2006, New Annual, $100,027
     
  • Spencer, Frederick A. (McMaster University)
    Clinical epidemiology and management of cardiovascular and venous thromboembolic disease
    2007, Career Investigator, $87,950
     
  • Spencer, Frederick A. (McMaster University)
    Fortinos Distinguished Scientist Award
    2007, Fortinos Award, $10,000
     
  • Stanimirovic, Danica B. (University of Ottawa)
    Astrocyte-endothelial cell interactions in hypoxia: role of P1GF in hypoxia-induced brain angiogenesis
    2006, Renewal, $73,586
     
  • Steinman, David A. (University of Toronto)
    Image-based modelling of hemodynamics and cerebrovascular disease
    2004, Career Investigator, $87,950
     
  • Sugita, Shuzo (University Health Network)
    Roles for CAPS1 in loading, storage and secretion of catecholamines in pheochromocytoma cells
    2007, New Annual, $64,500
     
  • Sun, Jiangfeng (University of Ottawa Heart Institute)
    Role of estrogen receptor beta in endothelial progenitor cell-mediated vascualr repair
    2007, Fellowship, $47,500
     
  • Suskin, Neville (London Health Sciences Centre)
    Comprehensive cardiac rehabilitation programming for patients following transient ischemic attack
    2007, New Annual (Pending), $126,745
     
  • Suuronen, Erik J. (University of Ottawa Heart Institute)
    Recruitment of endogenous circulating progenitor cells for cardiac regeneration using acellular tissue-engineered biomatrices
    2007, New Annual, $94,333
     
  • Sweeney, Gary (York University)
    Direct effects of adiponectin on cardiomyocytes
    2007, Renewal, $70,250
     
  • Truong, Kevin (University of Toronto)
    Deciphering Ca2+ signaling between subcellular organelles using fluorescent protein biosensors expressed in living cells
    2007, 
    New Annual, $51,600
     
  • Tsushima, Robert G. (York University)
    Snare protein modulation of cardiac Kv channels
    2006, Renewal, $80,925
     
  • Tu, Jack V. (Sunnybrook Health Sciences Center)
    Improving the quality of heart and stroke care in Canada
    2005, Career Investigator, $87,950
     
  • Tuana, Balwant S. (University of Ottawa)
    SLMAPs: Sarcolemmal membrane associated proteins and E-C coupling
    2006, Renewal, $142,667
     
  • Van Arsdell, Glen S. (Hospital for Sick Children)
    Analysis of the mechanisms of altered systemic and cerebral oxygen transport in children with hypoplastic left heart syndrome undergoing stage I palliation
    2006, New Annual (Pending), $89,328
     
  • Van Arsdell, Glen S. (Hospital for Sick Children)
    The influence of postoperative systemic oxygen transport on neurologic outcomes in infants undergoing the Norwood procedure with a modified blalock-taussig shunt or a right ventricle-to-pulmonary artery shunt
    2007, New Annual (Pending), $59,150
     
  • Verma, Subodh (St. Michael's Hospital)
    ACE2: Novel regulator of endothelial function and atherosclerosis
    2007, New Annual, $105,809
     
  • Waddell, Thomas K. (University Health Network)
    The role of galectin-3 in xenograft rejection
    2007, New Annual (Pending), $91,950
     
  • Wade, Terrance J. (Brock University)
    Social Determinants of Child Hypertension
    2007, Social Determinants (Pending), $100,085
     
  • Wang, Hui Di (Brock University)
    Reactive oxygen species mediates angiotensin II induced ET-1 release from vascular adventitial fibroblasts
    2007, New Annual, $57,010
     
  • Ward, Christopher A. (Queen's University)
    Cell-based gene therapy strategy to enhance neovascularization and healing of infarcted myocardium
    2007, Renewal, $92,952
     
  • Warkentin, Theodore E. (McMaster University)
    Heparin-induced thrombocytopenia
    2007, Renewal, $101,854
     
  • Weisel, Richard D. (University Health Network)
    Cardiac regeneration by cell transplantation
    2006, Renewal, $72,075
     
  • Weisel, Richard D. (University Health Network)
    Cardiac regeneration: improving the response to injury
    2007, Renewal, $77,182
     
  • Weitz, Jeffrey I. (McMaster University)
    Mechanisms of coronary catheter-induced clotting
    2006, Renewal, $116,670
     
  • Wells, Philip S. (Ottawa Health Research Institute)
    Thrombophilia: from bench to bedside to health economics and policy
    2004, Program, $250,000
     
  • Wen, Xiao-Yan (University Health Network)
    Investigation of lysophospatidic acid (LPA) generation and platelet function in newly developed lpdlr phospholipase deficient mice
    2007, New Annual, $87,232
     
  • Werstuck, Geoffrey H. (McMaster University)
    Investigating the role of glycogen synthase kinase (GSK)-3 in atherogenesis
    2007, Renewal, $82,688
     
  • Wijeysundera, Duminda N. (University Health Network)
    The EPIC (evaluating perioperative ischemia reduction by clonidine) study: a randomized, triple-blinded, placebo-controlled trial of combining clonidine with chronic beta-blockade in intermediate-to-high risk non-cardiac surgery
    2007, New Annual (Pending), $40,085
     
  • Yang, Burton B. (Sunnybrook Health Sciences Center)
    Roles of versican in mediating leukocyte and endothelial cell activites
    2006, Career Investigator, $87,950
     
  • Yang, Kaiping (University of Western Ontario)
    Early-life origins of visceral adiposity
    2007, New Annual, $85,192
     
  • Yao, Zemin (University of Ottawa Heart Institute)
    Interrelationship between hepatic lipase expression, proinflammatory cytokines, and HDL metabolism
    2007, Renewal, $86,360
     
  • Yao, Zemin (University of Ottawa)
    Analysis of non-truncation apoB mutations associated with human familial hypobetalipoproteinemia
    2007, Renewal, $82,538
     
  • Yarmo, Michelle (University of Ottawa)
    Macrophage-adipose cell interactions in obesity and cardiovascular disease
    2007, Master's Studentship (Pending), $18,000
     
  • Zandstra, Peter W. (University of Toronto)
    Controlling bioreactor condition to optimize regenerative potential of cardiomyocytes
    2007, New Annual, $89,725
     
  • Zhang, Xia (University of Ottawa)
    Poststroke treatment with cannabinoids for promoting neuronal regeneration
    2007, New Annual, $59,670
     
  • Zhang, Zhu-Xu (London Health Sciences Centre)
    Therapeutic potential and mechanism of double-negative regulatory T (DN-Treg) cells mediated tolerance in heart transplantation
    2007, New Annual, $78,294
     
  • Zimmerman, Deborah L. (Ottawa Health Research Institute)
    Control of hypertension in end stage renal disease, a randomized cross-over study comparing daily hemofiltration to conventional hemodialysis
    2007, New Annual (Pending), $53,327

     

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