Heart and Stroke Foundation of Canada/AstraZeneca Research Fellowship - Lapointe


Dr. Benoît Lapointe
University of Calgary 

Dr. Benoît Lapointe is researching ‘environmental cues’ within the brain that direct the course of the inflammatory response caused by strokes. His research is an invitation for us to think of stroke like an accident on a busy highway. Part of the system shuts down altogether; other parts are activated to clear the highway and remove the damage. And there are some well-intentioned interveners that just make everything a whole lot worse. They should be shown the red light and kept from the scene of the accident.
 
The particular focus of Dr. Lapointe’s research is cells called leukocytes. In ischemic stroke, leukocytes can act like these interveners that add to the damage caused by stroke. Leukocytes originate in the immune system as highly effective inflammatory agents to fight off infections. But in stroke, inflammation can add to the damage.
 
Dr. Lapointe hopes to develop a red light system to prevent or block leukocyte recruitment into the brain.
 
And that could substantially reduce stroke damage.
 
Dr. Lapointe is a postdoctoral fellow at the University of Calgary’s immunology research group, where he is currently pursuing studies on leukocyte recruitment in the central nervous system (related to multiple sclerosis and stroke). His work is supervised by Dr. Paul Kubes.
 
The Heart and Stroke Foundation of Canada and AstraZeneca Canada Inc. are proud to support talented investigators like Dr. Lapointe and look forward to the results of his work.
 
Supported by AstraZeneca Canada Inc.

 

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